特别提醒： 阅读填空题作答时，每个空格中只需填入一个大写英文字母，不要输入任何空格或标点符号，也不要填入小写字母。祝大家考出考成绩！(31-35题)In this section, you will read five sentences selected from an abstract. Each sentence is marked with a letter A, B,C,D or E. Please rearrange the sentences in proper order. Write down corresponding letter to fill in the blanks below IN ORDER . Write only ONE letter in ONE blank.(A) In mice, context-dependent pain hypersensitivity was abolished by castrating male mice, pharmacological blockade of the hypothalamic-pituitary-adrenal axis, or intracerebral or intrathecal injections of zeta inhibitory peptide (ZIP) known to block atypical protein kinase C (including the protein kinase Mz isoform). In humans, men, but not women, self-reported higher levels of stress when tested in a room previously associated with tonic pain.(B) These models provide a new, completely translatable means for studying the relationship between memory, pain, and stress.(C) Pain memories are hypothesized to be critically involved in the transition of pain from an acute to a chronic state.(D) We find that both mice and people become hypersensitive to acute, thermal nociception when tested in an environment previously associated with an aversive tonic pain experience. This sensitization persisted for at least 24 hr and was only present in males of both species.(E) To help elucidate the underlying neurobiological mechanisms of pain memory, we developed novel paradigms to study context-dependent pain hypersensitivity in mouse and human subjects, respectively.

题目：特别提醒： 阅读填空题作答时，每个空格中只需填入一个大写英文字母，不要输入任何空格或标点符号，也不要填入小写字母。祝大家考出考成绩！(31-35题)In this section, you will read five sentences selected from an abstract. Each sentence is marked with a letter A, B,C,D or E. Please rearrange the sentences in proper order. Write down corresponding letter to fill in the blanks below IN ORDER . Write only ONE letter in ONE blank.(A) In mice, context-dependent pain hypersensitivity was abolished by castrating male mice, pharmacological blockade of the hypothalamic-pituitary-adrenal axis, or intracerebral or intrathecal injections of zeta inhibitory peptide (ZIP) known to block atypical protein kinase C (including the protein kinase Mz isoform). In humans, men, but not women, self-reported higher levels of stress when tested in a room previously associated with tonic pain.(B) These models provide a new, completely translatable means for studying the relationship between memory, pain, and stress.(C) Pain memories are hypothesized to be critically involved in the transition of pain from an acute to a chronic state.(D) We find that both mice and people become hypersensitive to acute, thermal nociception when tested in an environment previously associated with an aversive tonic pain experience. This sensitization persisted for at least 24 hr and was only present in males of both species.(E) To help elucidate the underlying neurobiological mechanisms of pain memory, we developed novel paradigms to study context-dependent pain hypersensitivity in mouse and human subjects, respectively.